IMMA, CAS 2854-32-2

Formulation: A crystalline solid

Formal Name: 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-ethanone

Purity: ≥98%

Formula Markup: C23H23ClN2O4

Formula Weight: 426,9

Shelf life (days): 365

CAS Number: 2854-32-2

Notes: IMMA is a cannabinoid (CB) receptor 2 inverse agonist (Ki = 435 nM for recombinant human CB2).{4996,11066} It is selective for CB2 over CB1 receptors (Ki = >20 µM). IMMA (0.001-1 µM) reduces basal production of inositol phosphate and increases forskolin-induced accumulation of cAMP in HEK293 cells expressing human CB2 receptors.{11066} It inhibits LPS-induced nitric oxide (NO) and prostaglandin E2 (PGE2: Item No. 14010) production in J774 macrophages in a concentration-dependent manner.{57143}

• Artikelnummer: CAY70275-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 70275-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK