Iperoxo (iodide), CAS 247079-84-1

Formulation: A solid

Formal Name: 4-[(4,5-dihydro-3-isoxazolyl)oxy]-N,N,N-trimethyl-2-butyn-1-aminium, monoiodide

Purity: ≥98%

Formula Markup: C10H17N2O2 • I

Formula Weight: 324,2

Shelf life (days): 1460

CAS Number: 247079-84-1

Notes: Iperoxo is an agonist of muscarinic acetylcholine receptors.{48128,42728} It stimulates [35S]GTPγS binding to CHO cell membranes expressing human M2 muscarinic receptors and cell membranes expressing M4 muscarinic receptors (EC50s = 2.12 and 8.47 nM, respectively).{48128} Iperoxo induces M1-dependent inhibition of the twitch response in electrically-stimulated isolated rabbit vas deferens (pD2 = 9.87) and M3-mediated contraction of isolated guinea pig ileum (pD2 = 9.78).{42728} In vivo, iperoxo reduces formalin-induced paw licking and acetic acid-induced writhing in mice (ED50s = 0.004 and 0.001 mg/kg, respectively).{42729}

• Artikelnummer: CAY27235-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27235-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK