Ipratropium (bromide), CAS 22254-24-6

Formulation: A crystalline solid

Formal Name: (3-endo,8-syn)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane, monobromide

Purity: ≥95%

Formula Markup: C20H30NO3 • Br

Formula Weight: 412,4

Shelf life (days): 1460

CAS Number: 22254-24-6

Notes: Ipratropium is a muscarinic receptor antagonist (IC50s = 2.9, 2, and 1.7 nM for M1, M2, and M3 receptors, respectively).{47807} It inhibits acetylcholine-induced bronchospasm in anesthetized guinea pigs (EC50 = 68 μg/ml). Aerosolized ipratropium (0.2 mg/20 ml) prevents increases in airway resistance in a rat model of cadmium inhalation-induced chronic pulmonary inflammation with airspace enlargement and reduces neutrophil counts and total cell numbers in bronchoalveolar lavage fluid (BALF) and airspace enlargement in lungs when administered in combination with formoterol (Item No. 15584).{47808} Formulations containing ipratropium have been used in the treatment of bronchospasm associated with chronic obstructive pulmonary disease.

• Artikelnummer: CAY29423-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29423-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK