Isoxsuprine-d6 (hydrochloride), CAS 2706004-35-3

Formulation: A solid

Formal Name: 4-(1-hydroxy-2-((1-phenoxypropan-2-yl-1,1,2,3,3,3-d6)amino)propyl)phenol, monohydrochloride

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C18H17D6NO3 • HCl

Formula Weight: 343,9

Shelf life (days): 1460

CAS Number: 2706004-35-3

Notes: Isoxsuprine-d6 is intended for use as an internal standard for the quantification of isoxsuprine (Item No. 20688) by GC- or LC-MS. Isoxsuprine is an adrenergic receptor modulator that has α-adrenergic receptor (α-AR) antagonist and β-AR agonist properties.{48236,48237} It induces vasodilation of isolated equine common digital artery strips precontracted with norepinephrine, indicating an α-AR effect, and induces relaxation of isolated fowl cecum, an effect that can be blocked by the β-AR antagonist propranolol (Item Nos. 23349 / 17291).{48237,32760} Isoxsuprine has antinociceptive effects in an acetic acid writhing test in mice.{32759} It also inhibits oxytocin-induced contractions in isolated rat uterus (IC50 = 9.15 µM).{48238} It delays labor onset in rats by 31.63 hours when administered at a dose of 10 mg/kg per day on days 13 to 21 of gestation but increases heart rate with increasing concentration.

• Artikelnummer: CAY27847
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27847-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung