JNJ-42153605, CAS 1254977-87-1

Formulation: A crystalline solid

Formal Name: 3-(cyclopropylmethyl)-7-(4-phenyl-1-piperidinyl)-8-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyridine

Purity: ≥98%

Formula Markup: C22H23F3N4

Formula Weight: 400,4

Shelf life (days): 1460

CAS Number: 1254977-87-1

Notes: JNJ-42153605 is a positive allosteric modulator of metabotropic glutamate receptor 2 (mGluR2; EC50 = 17 nM in CHO cells expressing the human receptor).{48351} In vivo, JNJ-42153605 (3 mg/kg) inhibits mGluR2-mediated rapid eye movement (REM) sleep in rats. It also reverses phencyclidine-induced hyperlocomotion in mice (ED50 = 5.4 mg/kg).

• Artikelnummer: CAY21984-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21984-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK