Formulation: A crystalline solid
Formal Name: N-(4-amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]-benzamide, monohydrochloride
Purity: ≥98%
Formula Markup: C26H25N3O2 • HCl
Formula Weight: 448
Shelf life (days): 1460
CAS Number: 244218-51-7
Notes: JTC 801 is an antagonist of the nociceptin receptor (ORL1; Ki = 44.5 nM; IC50 = 94 nM) that is >100-, >100-, and >3-fold more selective for ORL1 over the related δ-, κ-, and µ-opioid receptors, respectively.{33471} It demonstrates anti-nociceptive effects in acute pain models in mice upon oral administration at 1 mg/kg.{33471}