Formulation: A crystalline solid
Formal Name: L-isoleucyl-L-alanyl-L-arginyl-L-arginyl-L-histidyl-L-prolyl-L-tyrosyl-L-phenylalanyl-L-leucine, trifluoroacetate salt
Purity: ≥95%
Formula Markup: C56H85N17O11 • XCF3COOH
Formula Weight: 1172,4
Shelf life (days): 1460
Notes: Kinetensin is a nonapeptide that has been found in pepsin-treated human plasma.{57526} It binds to neurotensin receptors in HT-29 cells and mouse brain (Kis = 1,396 and 149.6 nM, respectively, in radioligand binding assays) but does not induce the accumulation of intracellular calcium in HT-29 cells (EC50 = >10,000 nM).{57527} It induces histamine release in isolated rat peritoneal mast cells with an EC50 value of approximately 10 µM.{57528} Intradermal administration of kinetensin induces vascular permeability in rats.