L-156,602, CAS 125228-51-5

Formulation: A solid

Formal Name: (3S)-3-hydroxy-N-[(2S)-2-hydroxy-1-oxo-2-[(2R,5R,6R)-tetrahydro-2-hydroxy-6-methyl-5-[(2S)-2-methylbutyl]-2H-pyran-2-yl]propyl]-L-leucyl-(3R)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-L-alanylglycyl-(3S)-hexahydro-3-pyridazinecarbonyl-N-hydroxy-D-alanine, (6→13)-lactone

Purity: ≥95%

Formula Markup: C38H64N8O13

Formula Weight: 841

Shelf life (days): 1460

CAS Number: 125228-51-5

Notes: L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 µg/L in a radioligand binding assay using neutrophil membranes).{38590} It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria.{38591} L-156,602 has anti-inflammatory activity in mice, decreasing inflammation induced by muramyl dipeptide (MDP) when administered at a dose of 0.5 mg/kg and by concanavalin A (Item No. 14951) at doses of 0.25 and 0.5 mg/kg.{38592}

• Artikelnummer: CAY23896-2,5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23896-2.5
• Green Labware: Nein
• Verpackungseinheit: 2.5 mg
• Mengeneinheit: STK