L-701,324, CAS 142326-59-8

Formulation: A crystalline solid

Formal Name: 7-chloro-4-hydroxy-3-(3-phenoxyphenyl)-2(1H)-quinolinone

Purity: ≥98%

Formula Markup: C21H14ClNO3

Formula Weight: 363,8

Shelf life (days): 1460

CAS Number: 142326-59-8

Notes: L-701,324 is an NMDA receptor antagonist.{57099} It inhibits NMDA-induced currents in rat cortical neurons (Ki = 5.4 nM). L-701,324 inhibits seizures induced by N-methyl-DL-aspartate, pentylenetetrazole (PTZ; Item No. 18682), or electroshock, as well as audiogenic seizures in mice (ED50s = 3.5, 2.8, 1.4, and 0.96 mg/kg, respectively).{57100} It reduces the number of audiogenic seizures in a rat model of ethanol-induced withdrawal seizures when administered at a dose of 5 mg/kg.{57101} L-701,324 (2.5 and 5 mg/kg) reduces amphetamine-induced hyperactivity in rats.{57102}

• Artikelnummer: CAY30687-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30687-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK