L-Cysteinesulfinic Acid (hydrate), CAS 207121-48-0,

Formulation: A crystalline solid

Formal Name: 3-sulfino-L-alanine, monohydrate

Purity: ≥95%

Formula Markup: C3H7NO4S • H2O

Formula Weight: 171,2

Shelf life (days): 1460

CAS Number: 207121-48-0,

Notes: L-Cysteinesulfinic acid is an excitatory amino acid and agonist of metabotropic glutamate receptors (mGluRs).{49465,49466} It increases intracellular inositol phosphate levels in CHO cells expressing mGluR1, mGluR5, or mGluR8 (EC50s = 120, 30, and 110 μM, respectively) and inhibits forskolin-induced cAMP production in CHO cells expressing mGluR2 or mGluR6 and hamster kidney cells expressing mGluR4 (EC50s = 100, 100, and 2,000 μM, respectively).{49466} It selectively binds to mGluR1α (Ki = 3,510 nM) over adrenergic, dopamine, histamine, muscarinic, nicotinic, or serotonin receptors (Kis = >10,000 nM for all). L-Cysteinesulfinic acid (1 mM) decreases mean arterial blood pressure and heart rate in rats when microinjected into the nucleus tractus solitarius (NTS).{49465} L-Cysteinesulfinic acid can be formed via oxidation of L-cysteine by reactive oxygen species (ROS), and conversion of cysteine to L-cysteinesulfinic acid in cysteine-containing peptide probes has been used to measure oxidative stress.{49467}

• Artikelnummer: CAY29597-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29597-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK