Lanreotide (acetate), CAS 127984-74-1

Formulation: A solid

Formal Name: 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-cyclic (2→7)-disulfide, L-threoninamide, acetate

Purity: ≥98%

Formula Markup: C54H69N11O10S2 • XC2H4O2

Formula Weight: 1096,3

Shelf life (days): 1460

CAS Number: 127984-74-1

Notes: Lanreotide is a peptide analog of somatostatin that binds to somatostatin receptors (SSTRs) with a higher affinity for the somatostatin subgroup 2 receptors SST2, SST3, and SST5 (IC50s = 0.5-1.8, 43-107, and 5.6-32 nM, respectively) than for the subgroup 1 receptors, SST1 and SST4 (IC50s = 500-2,330 and 66-2,100 nM, respectively).{36315} Lanreotide (100 nM) inhibits the release of growth hormone from patient-derived pituitary adenoma cells in vitro.{36316} It also inhibits tumor growth in human small cell lung cancer (SCLC) mouse xenograft models when administered at a dose of 250 µg, twice daily.{36317} Formulations containing lanreotide have been used in the treatment of acromegaly and neuroendocrine tumors.

• Artikelnummer: CAY24084-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24084-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK