(Leu31,Pro34) Neuropeptide Y (human) (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: 31-L-leucine-34-L-proline-neuropeptide Y (human), trifluoroacetate salt

Purity: ≥95%

Formula Markup: C189H284N54O56S • XCF3COOH

Formula Weight: 4240,7

Shelf life (days): 1460

Notes: [Leu31,Pro34] Neuropeptide Y (NPY) is an agonist of the NPY receptors Y1 and Y5 with Ki values of 0.11 and 0.17 nM, respectively, for human and 0.08 and 0.18 nM, respectively, for rhesus monkey receptors.{41533} It reduces forskolin-induced cAMP accumulation in L-M(TK-) cells expressing human and rat Y4 receptors (EC50s = 29.5 and 2.95 nM, respectively). {41534} It also binds to rhesus monkey Y2 and mouse Y6 receptors (Kis = 410 and 9.7 nM, respectively).{41533,41536} In vitro, [Leu31,Pro34] NPY increases cellular protein mass by 25% in rat ventricular cardiomyocytes when used at a concentration of 10 nM.{41537} In vivo, [Leu31,Pro34] NPY (0.7-7 nmol, i.c.v.) increases food intake in rats.{41538}

• Artikelnummer: CAY24712-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24712-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK