Lidocaine-d10, CAS 851528-09-1

Formulation: A crystalline solid

Formal Name: 2-[di(ethyl-d5)amino]-N-(2,6-dimethylphenyl)-acetamide

Purity: ≥99% deuterated forms (d1-d10)

Formula Markup: C14H12D10N2O

Formula Weight: 244,4

Shelf life (days): 1460

CAS Number: 851528-09-1

Notes: Lidocaine-d10 is intended for use as an internal standard for the quantification of lidocaine by GC- or LC-MS. Lidocaine is an inhibitor of voltage-gated sodium channels (Navs) and a local anesthetic.{58904,58905,58906} It inhibits Nav1.2 (Ki = 11 µM), adult and neonatal Nav1.5 (IC50s = 380.1 and 360 µM, respectively), and Nav1.7 and Nav1.8 channels (IC50s = 450 and 104 µM, respectively) expressed in Xenopus oocytes. Topical administration of lidocaine (1-2%) reduces escape behavior in a rhesus monkey model of noxious electrical cutaneous pain.{58907} Formulations containing lidocaine have been used as local and regional anesthetics.

• Artikelnummer: CAY35066-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35066-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung