Lipid A Monophosphoryl from Salmonella minnesota R595

Formulation: A lyophilized powder

Shelf life (days): 1460

Notes: Lipid A monophosphoryl from Salmonella minnesota R595 is a non-toxic fragment of lipopolysaccharide (LPS) extracted from wild-type S. minnesota R595 and a TRIF biased toll-like receptor 4 (TLR4) agonist.{39965} Lipid A monophosphoryl induces T cell clonal expansion and TRIF-dependent production of G-CSF, IL-10, IP-10, and MCP-1 but has no effect on MyD88-dependent production of the inflammatory cytokines IL-1β, IL-6, MIP-1α, and IFN-γ in mice, indicating decreased potential for inflammatory toxicity compared to LPS and use as a non-toxic vaccine adjuvant.

• Artikelnummer: CAY25848
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25848-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK