LSN2814617, CAS 1313498-08-6

Formulation: A solid

Formal Name: 3-(1,1-dimethylethyl)-7-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyridine

Purity: ≥98%

Formula Markup: C18H20FN5O

Formula Weight: 341,4

Shelf life (days): 1460

CAS Number: 1313498-08-6

Notes: LSN2814617 is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5).{34521} It potentiates glutamate-induced calcium mobilization in MCB3901 cells expressing human mGluR5 (EC50 = 52 nM). LSN2814617 increases rat hippocampal mGluR5 receptor occupancy (ED50 = 13 mg/kg). It increases wakefulness and decreases non-rapid eye movement (NREM) and REM sleep in rats when administered at doses of 0.3, 1, and 3 mg/kg.

• Artikelnummer: CAY33607-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33607-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK
• Methode: Reinstoffe