Lumateperone (tosylate), CAS 1187020-80-9

Formulation: A solid

Formal Name: 1-(4-fluorophenyl)-4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)butan-1-one 4-methylbenzenesulfonic acid

Purity: ≥98%

Formula Markup: C24H28FN3O • C7H8O3S

Formula Weight: 565,7

Shelf life (days): 1460

CAS Number: 1187020-80-9

Notes: Lumateperone is an atypical antipsychotic.{58652} It selectively binds to the serotonin (5-HT) receptor subtype 5-HT2A over 5-HT1A and 5-HT2C receptors (Kis = 0.54, 1,480, and 173 nM, respectively). Lumateperone also binds to dopamine D1, D2, and D4 receptors (Kis = 52, 32, and 108 nM, respectively), α1A- and α1B-adrenergic receptors (Kis = 73 and 31 nM, respectively), and the 5-HT transporter (SERT; Ki = 61 nM). It reduces head-twitch behavior induced by the 5-HT2A agonist quipazine in rats (ED50 = 0.12 mg/kg). Formulations containing lumateperone have been used in the treatment of schizophrenia.

• Artikelnummer: CAY34541-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34541-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK