LY171883, CAS 88107-10-2

Formulation: A crystalline solid

Formal Name: 1-[2-hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)butoxy]phenyl]-ethanone

Purity: ≥98%

Formula Markup: C16H22N4O3

Formula Weight: 318,4

Shelf life (days): 1460

CAS Number: 88107-10-2

Notes: LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor.{1741} Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 µM, respectively.{1741} LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 µM) and various guinea pig tissues (IC50s range from 6.9-209 µM).{1741} At a concentration of 50-100 µM, LY171883 binds to the PPARγ nuclear receptor, inducing adipogenesis in cultured NIH3T3 fibroblasts.{1618,1425}

• Artikelnummer: CAY70710-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 70710-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK