M8-B (hydrochloride), CAS 883976-12-3

Formulation: A crystalline solid

Formal Name: N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide, monohydrochloride

Purity: ≥98%

Formula Markup: C22H24N2O3S • HCl

Formula Weight: 433

Shelf life (days): 1460

CAS Number: 883976-12-3

Notes: M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).{34008} It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.{34008}

• Artikelnummer: CAY21646-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21646-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK