Mabuterol, CAS 56341-08-3

Formulation: A crystalline solid

Formal Name: 4-amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)-benzenemethanol

Purity: ≥98%

Formula Markup: C13H18ClF3N2O

Formula Weight: 310,7

Shelf life (days): 1460

CAS Number: 56341-08-3

Notes: Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR).{36154,36155,36156} It induces relaxation of isolated tracheal muscle in guinea pigs and inhibits bronchoconstriction in a guinea pig model of experimental asthma.{36155} Administration of mabuterol decreases blood pressure and increases heart rate in a dose-dependent manner in rats, cats, and dogs.{36156} These effects are reversed by the selective β2-AR antagonist ICI 118551 (Item No. 15591), indicating mabuterol is acting at β2-ARs.{36154} At concentrations ≥1 μM, mabuterol acts as a β1-AR antagonist in isolated dog right atria.

• Artikelnummer: CAY23246-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23246-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK