MBX-8025 (sodium salt)

MBX-8025 (sodium salt)
Artikelnummer
CAY28761-1
Verpackungseinheit
1 mg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
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Formulation: A crystalline solid

Formal Name: (R)-2-(4-((2-ethoxy-3-(4-(trifluoromethyl)phenoxy)propyl)thio)-2-methylphenoxy)acetate, monosodium salt

Purity: ≥95%

Formula Markup: C21H22F3O5S • Na

Formula Weight: 466,4

Shelf life (days): 1460

Notes: MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).{53238} It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).{53239} It also decreases serum alanine transaminase (ALT), as well as serum and hepatic cholesterol and triglyceride, levels and reduces markers of NASH in the same model.
Mehr Informationen
Artikelnummer CAY28761-1
Hersteller Cayman Chemical
Hersteller Artikelnummer 28761-1
Green Labware Nein
Verpackungseinheit 1 mg
Mengeneinheit STK
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