Meclizine-d8 (hydrochloride), CAS 1432062-16-2

Formulation: A solid

Formal Name: 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine-2,2,3,3,5,5,6,6-d8, dihydrochloride

Purity: ≥99% deuterated forms (d1-d8)

Formula Markup: C25H19ClD8N2 • 2HCl

Formula Weight: 471,9

Shelf life (days): 1460

CAS Number: 1432062-16-2

Notes: Meclizine-d8 is intended for use as an internal standard for the quantification of meclizine (Item No. 14615) by GC- or LC-MS. Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM).{23220} Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung.{46070} Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.

• Artikelnummer: CAY26444-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26444-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung