Mepenzolate (bromide), CAS 76-90-4

Formulation: A solid

Formal Name: 3-[(2-hydroxy-2,2-diphenylacetyl)oxy]-1,1-dimethyl-piperidinium, monobromide

Purity: ≥95%

Formula Markup: C21H26NO3 • Br

Formula Weight: 420,3

Shelf life (days): 1460

CAS Number: 76-90-4

Notes: Mepenzolate is an antagonist of muscarinic (M) acetylcholine receptors (Kis = 0.68 and 2.6 nM for human M2 and M3 receptors, respectively).{41272} It has antispasmodic activity in the gastrointestinal tract of anesthetized cats and dogs when administered at a dose of 0.5 mg/kg.{41273} Mepenzolate decreases airspace enlargement induced by elastase or cigarette smoke and reduces respiratory dysfunction in a mouse model of chronic obstructive pulmonary disease (COPD).{41274} It also reduces oxidative stress, decreases the expression of IL-1β, IL-6, and TNF-α, and increases the expression of TGF-β1, IGF-1, and VEGF in a diabetic wound healing mouse model.{41275}

• Artikelnummer: CAY23717-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23717-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK