Mesoridazine, CAS 5588-33-0

Formulation: A solution in acetonitrile

Formal Name: 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine

Purity: ≥95%

Formula Markup: C21H26N2OS2

Formula Weight: 386,6

Shelf life (days): 730

CAS Number: 5588-33-0

Notes: Mesoridazine is an active metabolite of the typical antipsychotic thioridazine (Item No. 14400).{56193,56195} It is formed via sulfoxidation of thioridazine by the cytochrome P450 (CYP) isoform CYP2D6 in human liver microsomes.{56194} It binds to histamine H1, dopamine D2, muscarinic acetylcholine, and α1- and α2-adrenergic receptors (Kds = 1.8, 19, 69, 2, and 1,600 nM, respectively).{56195} Mesoridazine (10, 30, and 45 mg/kg, i.p.) prevents mescaline-induced hyperactivity in mice.{56196}

• Artikelnummer: CAY31370-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31370-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK