Metaproterenol (hemisulfate), CAS 5874-97-5

Formulation: A crystalline solid

Formal Name: 5-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-1,3-benzenediol, hemisulfate

Purity: ≥98%

Formula Markup: C11H17NO3 • 1/2H2SO4

Formula Weight: 260,3

Shelf life (days): 1460

CAS Number: 5874-97-5

Notes: Metaproterenol is a β2-adrenergic receptor (β2-AR) agonist with bronchodilator actions.{40372} It inhibits TGF-α-induced hepatocyte DNA synthesis and proliferation in vitro (IC50 = 15 nM), an effect that is reversed by the β2-AR antagonist butoxamine but not the β1-AR antagonist metoprolol (Item No. 15429).{40371} Metaproterenol dose-dependently relaxes lung strips and increases heart rate and inotropy of right atria and left atria, respectively, isolated from guinea pig (pD2s = 6.4, 7.08, and 6.61, respectively).{40373} Formulations containing metaproterenol were previously used as long-acting bronchodilators for the treatment of asthma.

• Artikelnummer: CAY23611-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23611-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK