Mexiletine (hydrochloride), CAS 5370-01-4

Formulation: A solid

Formal Name: 1-(2,6-dimethylphenoxy)-2-propanamine, monohydrochloride

Purity: ≥98%

Formula Markup: C11H17NO • HCl

Formula Weight: 215,7

Shelf life (days): 1460

CAS Number: 5370-01-4

Notes: Mexiletine is a voltage-gated sodium channel blocker and class Ib antiarrhythmic agent that preferentially binds to open/inactive channels.{40451} It inhibits aconitine-induced dysrhythmias in mice with ED50 values of 57 and 107 mg/kg for intraperitoneal and oral administration, respectively.{40452} Mexiletine decreases or inhibits conduction across the Purkinje fiber-muscle junction, shortens action potential duration, and decreases the refractory period when used at concentrations less than 5 µg/ml in isolated canine Purkinje fiber and ventricular muscle preparations.{40453}

• Artikelnummer: CAY23782-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23782-5
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK