ML-145, CAS 1164500-72-4

Formulation: A solid

Formal Name: 2-hydroxy-4-[[4-[(5Z)-5-[(2E)-2-methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidinyl]-1-oxobutyl]amino]-benzoic acid

Purity: ≥98%

Formula Markup: C24H22N2O5S2

Formula Weight: 482,6

Shelf life (days): 1460

CAS Number: 1164500-72-4

Notes: ML-145 is an antagonist of G protein-coupled receptor 35 (GPR35).{58378} It inhibits β-arrestin recruitment induced by the GPR35 agonists zaprinast (Item No. 10010421), cromolyn (Item No. 21379), and pamoic acid (Item No. 13946) in HEK293 cells expressing the human receptor (EC50s = 26, 22, and 8.3 nM, respectively). ML-145 inhibits constitutive and agonist-mediated D-myo-inositol-1-phosphate (IP1) accumulation in cells expressing human, but not rat, GPR35 in a concentration-dependent manner.

• Artikelnummer: CAY33534-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33534-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK