Moxonidine, CAS 75438-57-2

Formulation: A crystalline solid

Formal Name: 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine

Purity: ≥95%

Formula Markup: C9H12ClN5O

Formula Weight: 241,7

Shelf life (days): 1460

CAS Number: 75438-57-2

Notes: Moxonidine is an imidazoline 1 (I1) receptor agonist (Ki = 56 nM in a radioligand binding assay).{47043} It is also an agonist of the α2A-adrenergic receptor (α2A-AR; Ki = 150 nM in a radioligand binding assay). It is selective for I1 and α2A-AR receptors over α1-, α2B, and α2C-ARs (Kis = >30,000, 1,000, and 2,000 nM, respectively). Moxonidine decreases mean arterial pressure in spontaneously hypertensive rats when administered at a dose of 0.2 nmol injected into the rostral ventrolateral medulla oblongata (RVLM).{47044} It also reduces blood pressure in cynomolgus monkeys when administered at a dose of 167 µg/kg.{47043}

• Artikelnummer: CAY25639-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25639-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK