N-desmethyl Diltiazem (hydrochloride), CAS 130606-60-9

Formulation: A solid

Formal Name: 3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-1,5-benzothiazepin-4(5H)-one, monohydrochloride

Purity: ≥90%

Formula Markup: C21H24N2O4S • HCl

Formula Weight: 437

Shelf life (days): 1460

CAS Number: 130606-60-9

Notes: N-desmethyl Diltiazem is an active metabolite of the calcium channel inhibitor diltiazem.{69126} It is formed from diltiazem by the cytochrome P450 (CYP) isoforms CYP3A4, CYP3A5, and CYP3A7.{25992} N-desmethyl Diltiazem binds to isolated rat cerebral cortex homogenates (IC50 = 323 nM) and inhibits spontaneous contractions in isolated rat portal veins (IC50 = 489 nM).{69126} It has been found as a contaminant in fresh water.{69127}

• Artikelnummer: CAY34977-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34977-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe