N-Formyl-Met-Leu-Phe, CAS 59880-97-6

Formulation: A crystalline solid

Formal Name: N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Purity: ≥98%

Formula Markup: C21H31N3O5S

Formula Weight: 437,6

Shelf life (days): 1460

CAS Number: 59880-97-6

Notes: N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPRs; Ki = 0.8 pM), which are mainly localized on polymorphonuclear and mononuclear phagocytes.{34517} Activation of FPRs by fMLF leads to cellular activation, which is characterized by cellular polarization, chemotaxis, and release of proteolytic enzymes.{34518} fMLF induces contractions in isolated guinea pig jejunum (EC50 = 11 nM), proximal colon (EC50 = 3.5 nM), and distal colon (EC50 = 2.2 nM).{34516} In vitro, fMLF induces neurotransmitter release from enteric motor neurons.

• Artikelnummer: CAY21495-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21495-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK