N6-Cyclohexyladenosine, CAS 36396-99-3

Formulation: A crystalline solid

Formal Name: N-cyclohexyl-adenosine

Purity: ≥98%

Formula Markup: C16H23N5O4

Formula Weight: 349,4

Shelf life (days): 1460

CAS Number: 36396-99-3

Notes: N6-Cyclohexyladenosine is an adenosine receptor agonist.{48560} It selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM). N6-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC25s = 2.4 and 4.2 μg/kg, respectively).{48560} N6-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion.{52007} N6-Cyclohexyladenosine also decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.).{52008}

• Artikelnummer: CAY28427-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28427-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK