Nemadipine A, CAS 54280-71-6

Formulation: A crystalline solid

Formal Name: 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester

Purity: ≥98%

Formula Markup: C19H18F5NO4

Formula Weight: 419,3

Shelf life (days): 1460

CAS Number: 54280-71-6

Notes: Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in the C. elegans genome.{38802} It also inhibits L-type calcium channels in chick ciliary neurons. Nemadipine A increases TRAIL-induced cytotoxicity and synergistically enhances caspase-8 and caspase-3 activation in a concentration-dependent manner in H1299 lung adenocarcinoma cells.{38803} It also decreases Survivin expression when used alone or in combination with TRAIL in A549 cells.

• Artikelnummer: CAY21689-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21689-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK