Neurokinin B (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: L-α-aspartyl-L-methionyl-L-histidyl-L-α-aspartyl-L-phenylalanyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-methioninamide, 2,2,2-trifluoroacetate

Purity: ≥95%

Formula Markup: C55H79N13O14S2 • XCF3COOH

Formula Weight: 1210,4

Shelf life (days): 1460

Notes: Neurokinin B is a tachykinin peptide agonist of the neurokinin-3 receptor (NK3; Ki = 0.8 nM).{41381,28052} In vitro, neurokinin B dose-dependently induces calcium mobilization in HEK293 cells expressing NK3 (EC50 = 0.5 nM), an effect inhibited by NK3 antagonists. Neurokinin B potentiates electrically-induced contractions in rat vas deferens and increases vasodilation in rat hind paw in a dose-dependent manner.{41381} In juvenile male rhesus monkeys, neurokinin B (100 µg, i.v.) stimulates luteinizing hormone (LH) release and acts within the hypothalamus, suggesting a role in initiating puberty.{37409}

• Artikelnummer: CAY24542-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24542-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK