Neuromedin U-23 (rat) (trifluoroacetate salt)

Formulation: A solid

Formal Name: L-tyrosyl-L-lysyl-L-valyl-L-asparaginyl-L-α-glutamyl-L-tyrosyl-L-glutaminylglycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-serylglycylglycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C124H180N34O31 • XCF3COOH

Formula Weight: 2643

Shelf life (days): 1460

Notes: Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.{28859} It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50 = 0.17 nM for the human receptor in a calcium mobilization assay using HEK293 cells) and NMUR2 (EC50 = ~1.4-2 nM for arachidonic acid release in CHO cells expressing the human receptor).{60693,60694} NMU-23 (1 µM) induces contractions in isolated rat colon smooth muscle strips.{60695} It decreases body weight and food intake and increases core body temperature in mice when administered at a dose of 36 µg/animal.{37637} Intrathecal administration of NMU-23 decreases the mechanical pain threshold in the von Frey test in rats.{60696}

• Artikelnummer: CAY34430-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34430-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK