Formulation: An oil
Formal Name: 3-[(2S)-1-methyl-2-pyrrolidinyl]-pyridine
Purity: ≥95%
Formula Markup: C10H14N2
Formula Weight: 162,2
Shelf life (days): 1460
CAS Number: 54-11-5
Notes: (–)-Nicotine is an alkaloid that has been found in tobacco.{26727} It is an agonist at neuronal nicotinic acetylcholine receptors (nAChRs) and binds to α3β4 and α4β2 subunit-containing nAChRs with Ki values of 481 and 11.1 nM, respectively.{26727,18814} Chronic exposure to (–)-nicotine results in increased expression of certain nAChRs, particularly α4β2 subunit-containing nAChRs.{48631} (–)-Nicotine has addictive properties.{18814,48631} Formulations containing (–)-nicotine have been used as smoking cessation aids for the relief of nicotine withdrawal symptoms.