Nilutamide-d6, CAS 1189477-66-4

Formulation: A solid

Formal Name: 5,5-bis(methyl-d3)-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione

Purity: ≥99% deuterated forms (d1-d6)

Formula Markup: C12H4D6F3N3O4

Formula Weight: 323,3

Shelf life (days): 1460

CAS Number: 1189477-66-4

Notes: Nilutamide-d6 is intended for use as an internal standard for the quantification of nilutamide (Item No. 23953) by GC- or LC-MS. Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor.{41485} It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro.{41484} It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg.{41486} Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer.

• Artikelnummer: CAY28694
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28694-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung