NP-118809, CAS 41332-24-5

Formulation: A solid

Formal Name: 1-[4-(diphenylmethyl)-1-piperazinyl]-3,3-diphenyl-1-propanone

Purity: ≥95%

Formula Markup: C32H32N2O

Formula Weight: 460,6

Shelf life (days): 1460

CAS Number: 41332-24-5

Notes: NP-118809 is an inhibitor of N-type voltage-gated calcium channels (IC50 = 0.11 µM).{68594} It is selective for N-type over L-type voltage-gated calcium channels and human-ether-a-go-go (hERG), also known as Kv11.1 (IC50s = 12.2 and 7.4 µM, respectively), as well as a panel of 112 other ion channels, receptors, and signaling targets at 10 µM. NP-118809 (25 mg/kg, i.p.) decreases the number of flinches in the second phase of the formalin test in a rat model of inflammatory pain.

• Artikelnummer: CAY37539-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37539-100
• Green Labware: Nein
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK