Oxcarbazepine-d4, CAS 1134188-71-8

Formulation: A solid

Formal Name: 10,11-dihydro-11-oxo-5H-dibenz[b,f]azepine-1,2,3,4-d4-5-carboxamide

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C15H8D4N2O2

Formula Weight: 256,3

Shelf life (days): 1460

CAS Number: 1134188-71-8

Notes: Oxcarbazepine-d4 is intended for use as an internal standard for the quantification of oxcarbazepine (Item No. 17340) by GC- or LC-MS. Oxcarbazepine is a prodrug form of the antiepileptic compound 10,11-dihydro-10-hydroxy carbamazepine (Item No. 18467).{25311,45753} It inhibits high-frequency repetitive firing of rat spinal cord neurons when used at a concentration of 1 µM.{45753} Oxcarbazepine protects against electroshock-induced tonic hindlimb extension (ED50s = 10-20 mg/kg), as well as seizures induced by pentylenetetrazole (PTZ; Item No. 18682) or picrotoxin (Item No. 20771) in rodents (ED50s = 23-30 and 150-250 mg/kg, respectively). Formulations containing oxcarbazepine have been used in the treatment of epileptic seizures.

• Artikelnummer: CAY29995
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29995-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung