Palmitoyl Serotonin, CAS 212707-51-2

Formulation: A neat solid

Formal Name: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-hexadecanamide

Purity: ≥98%

Formula Markup: C26H42N2O2

Formula Weight: 414,6

Shelf life (days): 365

CAS Number: 212707-51-2

Notes: Palmitoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid-type 1 (TRPV1) channel, reducing both acute and chronic peripheral pain.{18121,18122} The effects of replacing the arachidonoyl portion with the saturated 16-carbon palmitoyl moiety have not been studied. However, replacement of arachidonate with saturated 11- or 12-carbon fatty acids produces compounds that potently inhibit capsaicin-induced TRPV1 channel activation (IC50 = 0.76 μM) without blocking FAAH-mediated hydrolysis of arachidonoyl ethanolamine (IC50 > 50 μM).{18121}

• Artikelnummer: CAY9000630-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000630-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK