Parthenolide, CAS 20554-84-1

Formulation: A crystalline solid

Formal Name: 2,3,6,7,7aS,8,10aS,10bR-octahydro-1aR,5-dimethyl-8-methylene-(4E)-oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one

Purity: ≥98%

Formula Markup: C15H20O3

Formula Weight: 248,3

Shelf life (days): 1460

CAS Number: 20554-84-1

Notes: Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium). It inhibits the growth of the promastigote form of L. amazonensis (IC50 = 3.6 μg/ml).{20976} Parthenolide also induces apoptosis in cancer cells, at least in part by inhibiting NF-κB- and STAT-mediated anti-apoptotic gene transcription.{20973,20975} This compound has also been shown to block inflammation by inhibiting signaling through NF-κB.{20974} Inhibition of NF-κB by parthenolide can be achieved by direct binding of the pattern recognition receptor NOD2 by parthenolide.{20972}

• Artikelnummer: CAY70080-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 70080-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK