Phenytoin, CAS 57-41-0

Formulation: A crystalline solid

Formal Name: 5,5-diphenyl-2,4-imidazolidinedione

Purity: ≥98%

Formula Markup: C15H12N2O2

Formula Weight: 252,3

Shelf life (days): 1460

CAS Number: 57-41-0

Notes: Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin (Item No. 23889). Phenytoin is formed from fosphenytoin by tissue phosphatases.{39385} It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner.{38721} Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal slices (EC50s = 42.8 and 33.5 µM, respectively).{61191} It protects against seizures induced by maximal electroshock (MES) in mice (ED50 = 10 mg/kg).{61192} Formulations containing phenytoin have been used in the treatment of tonic-clonic seizures and status epilepticus.

• Artikelnummer: CAY24037-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24037-100
• Green Labware: Nein
• Verpackungseinheit: 100 g
• Mengeneinheit: STK