Piribedil, CAS 3605-01-4

Formulation: A solid

Formal Name: 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-pyrimidine

Purity: ≥98%

Formula Markup: C16H18N4O2

Formula Weight: 298,3

Shelf life (days): 1460

CAS Number: 3605-01-4

Notes: Piribedil is a dopamine receptor agonist.{56138,56139,56140,56141} It binds to dopamine D2, D3, and D4 receptors (IC50s = 1-1,000 nM in radioligand binding assays).{56138} Piribedil (1 and 10 mg/kg) enhances spontaneous object recognition in young adult rats and attenuates age-related memory impairments in the radial arm maze in mice.{56139} It reduces immobility time in the forced swim test in mice when administered at doses ranging from 0.63 to 10 mg/kg.{56140} Piribedil (0.3 mg/kg) decreases the number of premature and delayed responses in a response time test, indicating improved attentional function, in a rat model of Parkinson's disease induced by 6-OHDA (Item No. 25330) when administered in combination with L-DOPA (Item No. 13248).{56141}

• Artikelnummer: CAY30321-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30321-500
• Green Labware: Nein
• Verpackungseinheit: 500 mg
• Mengeneinheit: STK