(±)-Propranolol (hydrochloride), CAS 318-98-9

Formulation: A crystalline solid

Formal Name: 1-[(1-methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol, monohydrochloride

Purity: ≥98%

Formula Markup: C16H21NO2 • HCl

Formula Weight: 295,8

Shelf life (days): 1460

CAS Number: 318-98-9

Notes: (±)-Propranolol is a β-adrenergic receptor (β-AR) antagonist (Kds = 6.91, 0.832, and 117.49 nM for human β1-, β2-, and β3-ARs, respectively).{25151} It reduces mean blood pressure, resting heart rate, and contractility and increases AV conduction time in dogs.{30090} (±)-Propranolol restores normal sinus rhythm in dogs with ouabain-induced arrhythmias (ED50 = 3.8 mg/kg).{39376} It also acts as a non-specific serotonin receptor antagonist, reducing tranylcypromine/L-tryptophan-induced hyperactivity in rats.{25891} Formulations containing (±)-propranolol have been used for the treatment of hypertension, angina pectoris, and cardiac ischemia.

• Artikelnummer: CAY23349-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23349-10
• Green Labware: Nein
• Verpackungseinheit: 10 g
• Mengeneinheit: STK