Formulation: A solid
Formal Name: 4-[3-acetyl-2,5-dihydro-4-hydroxy-1-[2-(2-methyl-1H-indol-3-yl)ethyl]-5-oxo-1H-pyrrol-2-yl]-benzoic acid, methyl ester
Purity: ≥98%
Formula Markup: C25H24N2O5
Formula Weight: 432,5
Shelf life (days): 1460
CAS Number: 1560894-05-4
Notes: PYD-106 is a positive allosteric modulator of NR2C subunit-containing NMDA receptors (NMDARs).{48963} It enhances glutamate-induced maximal current responses in HEK293 cells expressing NR1/NR2C NMDA receptors (EC50 = 13 µM). PYD-106 is selective for NR2C subunit-containing NMDA receptors over NRA-, NR2B-, and NR2D-subunit containing NMDA receptors in Xenopus oocytes expressing NR1/NR2 heteromeric NMDA receptors at 30 µM.