Q94 (hydrochloride hydrate)

Formulation: A solid

Formal Name: 1-[(4-chlorophenyl)methyl]-2-(phenylmethyl)-1H-benzimidazole, monohydrochloride, hydrate

Purity: ≥98%

Formula Markup: C21H17ClN2 • HCl [XH2O]

Formula Weight: 369,3

Shelf life (days): 1460

Notes: Q94 is a Gαq signaling-biased antagonist of proteinase-activated receptor 1 (PAR1; IC50 = 916 nM).{57389,57391} It inhibits increases in intracellular calcium mobilization induced by thrombin or a PAR1-activating peptide, but not a PAR2-activating peptide, in HMEC-1 cells when used at concentrations of 1 and 10 μM.{57389} Q94 (5 mg/kg per day) decreases albuminuria in a mouse model of nephropathy induced by doxorubicin (Item No. 15007).{57390}

• Artikelnummer: CAY32857-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 32857-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK