(R)-4-Amino-3-hydroxybutyric Acid, CAS 7013-07-2

(R)-4-Amino-3-hydroxybutyric Acid, CAS 7013-07-2
Artikelnummer
CAY31532-100
Verpackungseinheit
100 mg
Hersteller
Cayman Chemical

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Formulation: A crystalline solid

Formal Name: (3R)-4-amino-3-hydroxy-butanoic acid

Purity: ≥95%

Formula Markup: C4H9NO3

Formula Weight: 119,1

Shelf life (days): 1460

CAS Number: 7013-07-2

Notes: (R)-4-Amino-3-hydroxybutyric acid is a GABA receptor modulator.{61092} It binds to GABAA and GABAB receptors (IC50s = 1 and 0.35 µM, respectively) and inhibits GABA uptake in rat brain synaptosomes (IC50 = 67 µM). (R)-4-amino-3-hydroxybutyric acid is also a GABAC receptor agonist that induces currents in a patch-clamp assay using Xenopus oocytes expressing the human receptor (EC50 = 19 µM).{61091} In vivo, (R)-4-amino-3-hydroxybutyric acid (20 mg/animal) inhibits electrical discharges in the amygdala in a cat model of N-amidinobenzamide-induced seizures.{61093}
Mehr Informationen
Artikelnummer CAY31532-100
Hersteller Cayman Chemical
Hersteller Artikelnummer 31532-100
Green Labware Nein
Verpackungseinheit 100 mg
Mengeneinheit STK
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