Radiprodil, CAS 496054-87-6

Radiprodil, CAS 496054-87-6
Artikelnummer
CAY29712-5
Verpackungseinheit
5 mg
Hersteller
Cayman Chemical

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Formulation: A solid

Formal Name: N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-α-oxo-1-piperidineacetamide

Purity: ≥98%

Formula Markup: C21H20FN3O4

Formula Weight: 397,4

Shelf life (days): 1460

CAS Number: 496054-87-6

Notes: Radiprodil is an antagonist of NR2B subunit-containing NMDA receptors (IC50 = 8 nM).{52284} It is selective for NR2B subunit-containing NMDA receptors over NR1 and NR2A subunit-containing NMDA receptors at 15 µM. Radiprodil (10 nM) reduces amyloid β (1-42) (Aβ42) and Aβ40-induced decreases in dendritic spine density in mouse hippocampal CA1 pyramidal neurons.{52285} Radiprodil (2 mg/kg) restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinson's disease.{47789}
Mehr Informationen
Artikelnummer CAY29712-5
Hersteller Cayman Chemical
Hersteller Artikelnummer 29712-5
Green Labware Nein
Verpackungseinheit 5 mg
Mengeneinheit STK
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