Raloxifene 4'-Glucuronide, CAS 182507-22-8

Formulation: A solid

Formal Name: 4-[6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl, β-D-glucopyranosiduronic acid

Purity: ≥95%

Formula Markup: C34H35NO10S

Formula Weight: 649,7

Shelf life (days): 1460

CAS Number: 182507-22-8

Notes: Raloxifene 4’-glucuronide is a metabolite of the selective estrogen receptor modulator raloxifene (Item No. 10011620).{42731} It is formed from raloxifene via the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A8, and UGT1A10.{42732} It binds to the estrogen receptor with an IC50 value of 370 nM.{42731} Raloxifene 4’-glucuronide inhibits the voltage-gated potassium channel Kv4.3 by 6.2 and 20.1% when used at concentrations of 10 and 30 µM, respectively.{42733}

• Artikelnummer: CAY27831
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27831-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK