Formulation: A solid
Formal Name: (E)-N-(2-(((5-((bis(methyl-d3)amino)methyl)furan-2-yl)methyl)thio)ethyl)-N'-methyl-2-nitroethene-1,1-diamine, monohydrochloride
Purity: ≥99% deuterated forms (d1-d6)
Formula Markup: C13H16D6N4O3S • HCl
Formula Weight: 356,9
Shelf life (days): 1460
CAS Number: 1185238-09-8
Notes: Ranitidine-d6 is intended for use as an internal standard for the quantification of ranitidine (Item No. 16939) by GC- or LC-MS. Ranitidine is a histamine H2 receptor antagonist.{27474} It reverses histamine-induced relaxation of isolated rat uterine horn (pA2 = 6.9) as well as histamine-induced increases in contraction frequency in isolated guinea pig right atrium (pA2 = 7.2). Ranitidine (0.03-3 mg/kg, i.v.) inhibits histamine-and pentagastrin-induced gastric acid secretion in a dose-dependent manner in anesthetized rats. Formulations containing ranitidine have been used in the treatment and prevention of heartburn and gastroesophageal reflux disease (GERD).