Ranitidine S-oxide, CAS 73851-70-4

Formulation: A solid

Formal Name: N′-[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]sulfinyl]ethyl]-N-methyl-2-nitro-1,1-ethenediamine

Purity: ≥90%

Formula Markup: C13H22N4O4S

Formula Weight: 330,4

Shelf life (days): 1460

CAS Number: 73851-70-4

Notes: Ranitidine S-oxide is a metabolite of the histamine H2 receptor antagonist ranitidine (Item No. 16939).{67071} It is formed via S-oxidation of ranitidine by flavin-containing monooxygenase 3 (FMO3) and FMO5.{67069} Ranitidine S-oxide is acutely cytotoxic to the aquatic species B. calyciflorus and C. dubia (LC50s = 4.51 and 7.85 mg/L, respectively), and it inhibits the reproduction of B. calyciflorus and C. dubia with chronic exposure (EC50s = 0.83 and 0.51 mg/L, respectively).{67070} It is mutagenic to S. typhimurium and genotoxic to E. coli when used at concentrations ranging from 0.312 to 0.625 µg/ml and 0.312 to 5 µg/ml, respectively.

• Artikelnummer: CAY35412-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 35412-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe