S-Sulfocysteine, CAS 1637-71-4

Formulation: A solid

Formal Name: S-sulfo-L-cysteine

Purity: ≥90%

Formula Markup: C3H7NO5S2

Formula Weight: 201,2

Shelf life (days): 1460

CAS Number: 1637-71-4

Notes: S-Sulfocysteine is an NMDA receptor agonist.{64749} It is selective for the NMDA receptor over the AMPA receptor in radioligand binding assays (EC50s = 8.2 and 59 µM, respectively). S-Sulfocysteine (200 µM) is cytotoxic to primary mouse neuronal cells.{64750} It induces calcium influx and activates calpain-dependent degradation of the post-synaptic scaffolding protein gephyrin when used at a concentration of 100 µM. S-Sulfocysteine (2 mM) increases swimming and seizure-like movements, indicating neurodegeneration, in zebrafish larvae when administered three days post-fertilization.{64748} Urinary and plasma levels of S-sulfocysteine are increased in patients with molybdenum cofactor deficiency (MoCD), an inborn error of metabolism characterized by neurodegeneration and early childhood death.{64750}

• Artikelnummer: CAY34559-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34559-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK
• Methode: Reinstoffe